Lower Price Supply High Purity Colistin Methanesulfonate Sodium Salt Powder CAS 8068-28-8 CAS NO.8068-28-8

English name: COLISTIN METHANESULFONATE SODIUM SALT

CAS number: 8068-28-8

Molecular formula: Unspecified

Molecular weight: 1749.82

EINECS Number: 232-516-9

Melting point:>228°C(dec.)

Storage conditions: 2-8°C

Solubility:H2O:soluble10mg/mL

Form: powder

Color: white to faintly beige

PH value: 6-8 (10mg/mLinH2O)

Water solubility: Freely soluble in water

Colistins are a group of polypeptide antibiotics produced by Bacillus polymyxa. Among them, polymyxins B and E have significant antibacterial activity against Gram-negative bacteria and are the first choice drugs for the treatment of Pseudomonas aeruginosa infection. The preparation method of colistin sodium methanesulfonate, comprising the following steps: (a) adjusting the pH of the colistin sulfate aqueous solution to 9-13 with ammonia water or sodium hydroxide solution, stirring and reacting for 1-3 hours with suction filtration, and the obtained filtration Deionized water is added to the cake to prepare a colistin suspension; (b) sodium hydroxymethanesulfonate is added to the above suspension, and the reaction is carried out for 1 to 24 hours at a temperature of 10 to 90°C; (c) The reaction solution generated in step b is separated and purified by a mixed resin composed of a gel-type styrene-based strong acid cation exchange resin and a macroporous acrylic-based weakly basic anion exchange resin; the amount of the mixed resin is based on colistin sulfate. The weight ratio to the mixed resin is 1:1.5-3.0; (d) drying the product obtained in step c.

Colistin sodium methanesulfonate is an organometallic compound that can be used as a pharmaceutical raw material.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.