Enalapril maleate CAS 76095-16-4 CAS NO.76095-16-4

Enalapril maleate is the second angiotensin converting enzyme inhibitor to reach the marketplace. Like captopril, the first entry in this area, enalapril is useful in the treatment of hypertension and congestive heart failure. It has a longer effective half-life than captopril, allowing once or twice-daily dosing, and appears to have a somewhat lower incidence of side effects.
The principle use of enalapril/enalaprilat in veterinary medicine at present is as a vasodilator in the treatment of heart failure. Recent studies have demonstrated that enalapril, particularly when used in conjunction with furosemide, does improve the quality of life in dogs with heart failure. It is not clear, however, whether it has any significant effect on survival times. It may also be of benefit in treating the effects associated with valvular heart disease (mitral regurgitation) and left to right shunts. It is being explored as adjunctive treatment in chronic renal failure and protein losing nephropathies.

Enalapril maleate is a potent angiotensin-converting enzyme (ACE) inhibitor without sulfhydryl group, which is hydrolyzed to Enalaprilat in vivo to inhibit ACE. Its mechanism of action is to inhibit the conversion of angiotensin I to angiotensin II, which reduces the tension of vascular smooth muscle, reduces the secretion of aldosterone, and reduces blood pressure. Its antihypertensive effect is 10 times stronger and longer lasting than captopril. Its antihypertensive effect is slow and long-lasting. Its hemodynamic effect is similar to that of captopril, which can reduce total peripheral vascular resistance and renal vascular resistance, and increase renal blood flow. Long-term application can reverse left ventricular hypertrophy and improve ventricular remodeling.

1. Renin-angiotensin-type high pressure drugs.

2. For renin-angiotensin antihypertensive drugs

3. Essential hypertension at all stages; renovascular hypertension; heart failure at all levels. For patients with symptomatic heart failure, this product is also suitable for improving the survival rate, delaying the progression of symptomatic heart failure, and reducing the risk of heart failure due to heart failure. hospitalization; prevention of symptomatic heart failure, for patients with asymptomatic left ventricular insufficiency, prevention of coronary ischemic events in patients with left ventricular insufficiency, this product is suitable for reducing the incidence of myocardial infarction and reducing the incidence of unstable angina pectoris hospitalization

Product Name Enalapril maleate
Appearance White powder
Molecular formula C24h32n2o9
Molecular Weight 492.525
Keywords API Raw Material Enalapril maleate;Enalapril maleate Powder;Enalapril maleate
24 months when properly stored
Storage Keep in a cool, dry, dark location

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
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Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.