API 99% Argatroban anhydrous CAS 74863-84-6 CAS NO.74863-84-6

English name: Argatroban

CAS number: 74863-84-6

Molecular formula: C23H36N6O5S

Molecular weight: 508.63

EINECS Number: 638-764-8

Melting point: 188-1890C

Boiling point: 777.2±70.0°C (Predicted)

Density: 1.47±0.1g/cm3(Predicted)

Storage conditions: Keep in dark place, Sealedindry, 2-8°C

Solubility: Soluble in DMSO (upto50mg/ml).

Acidity coefficient: (pKa) 10.44±0.40 (Predicted)

Form: White to off-white powder.

Color: White

Gatroban is a synthetic anticoagulant and a reversible competitive thrombin inhibitor, which has a strong selective inhibitory effect on thrombin and inhibits platelet aggregation caused by thrombin. The inhibitory effect on fibrin is weak. In vitro, inhibits thrombus generated in various thrombosis models. In experimental models, it has been confirmed that this drug is significantly more effective than heparin in preventing coronary thrombosis, and can competitively inhibit thrombin-induced platelet activation and aggregation. Unlike heparin, argatroban does not cause thrombocytopenia and does not further prolong bleeding time when aspirin is added. Preliminary studies have confirmed that this drug combined with aspirin to prevent coronary thrombosis is an effective combination. Argatroban is effective in unstable angina. The anticoagulant effect of this product does not require the cooperation of antithrombin III. It can be rapidly distributed in tissues, mainly in the liver, kidney and digestive tract. PBP is 35% to 60%. Metabolites are mainly compounds with aromatic rings and hydroxyl groups. About 50% are excreted in urine and feces 24 hours after administration, and most of them are excreted after 48 hours.

1, We offer competitive factory price for both wholesalers and retailers.
2, Fast reply for inquiries.
3, Stable Quality, high purity.
4, We offer EXW/FOB/CFR/DAP/DDP trade terms for your option.
5, Fast Delivery for shipment and Safe for destination custom clearance.
6, Free samples.
7, Free custom clearance with freight prepaid, delivery door to door.
8, More than 5 years export experience in this field.

English name: Argatroban

CAS number: 74863-84-6

Molecular formula: C23H36N6O5S

Molecular weight: 508.63

EINECS Number: 638-764-8

Argatroban is a synthetic anticoagulant and a reversible competitive thrombin inhibitor. It has a strong selective inhibitory effect on thrombin and inhibits platelet aggregation caused by thrombin. The inhibitory effect on fibrin is weak. In vitro, inhibits thrombus generated in various thrombosis models. In experimental models, it has been confirmed that this drug is significantly more effective than heparin in preventing coronary thrombosis, and can competitively inhibit thrombin-induced platelet activation and aggregation. Unlike heparin, argatroban does not cause thrombocytopenia and does not further prolong bleeding time when aspirin is added.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

We are at the exhibition every year.