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Home > Products >  CAS 66985-17-9 pratropium Bromide Ipratropium bromide monohydrate

CAS 66985-17-9 pratropium Bromide Ipratropium bromide monohydrate CAS NO.66985-17-9

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Keywords

  • Ipratropium bromide monohydrate
  • pratropium Bromide
  • Pharmaceutical intermediates

Quick Details

  • ProName: CAS 66985-17-9 pratropium Bromide Ipra...
  • CasNo: 66985-17-9
  • Molecular Formula: C20H32BrNO4
  • Appearance: White Powder
  • Application: Pharmaceutical intermediates
  • DeliveryTime: 2-3days
  • PackAge: Barrel or Drum
  • Port: Shenzhen
  • ProductionCapacity: 6000 Kilogram/Day
  • Purity: 99%+
  • Storage: room temperature
  • Transportation: By air or by sea
  • LimitNum: 1 Gram
  • Moisture Content: meet requirement
  • Impurity: meet requirement
  • Assay: 99%+
  • Shelf Life: 2 years
  • Appearance: White Powder

Superiority

Items Specifications Result
Appearance White or almost white, crystalline powder Almost white, crystalline powder
Melting point About 230ºC, with decomposition 227ºC~229ºC, with decomposition
Identification A Infrared absorption spectrophotometry. Comparison: ipratropium bromide CRS. Complies
Identification B Examine the chromatograms obtained in the test for impurity A. Results: the principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogra obtained with reference solution. Complies
Identification C To 5 ml of solution S(see tests), and 2 ml of dilute sodiumhydroxide solution R. No precipitate is formed. Complies
Identification D To about 1mg add 0.2ml of nitri c acid R and evaporate to dryness on a water-bath. Dissolve the residue in 2ml of actone R and add 0.1ml of a 30g/L solution of potassiumhydroxide R in methano l R. A violet colour develops. Complies
Identification E It gives reaction of bromides. Complies
Appearance of solution The solution is clear and not more intensely coloured then reference solution GY7. Complies
PH 5.0~7.5 6.2
Impurity A NMT0.1% Not detected
Related substances Impurity B, C: NMT 0.1%
Impurity D: NMT 0.05%
Unspecified impurities:for each impurity, NMT0.1%
Total: NMT 0.25%
Disregard limit: 0.03%
Disregard the peak due to the bromide ion.
Impurity B: Not detected;
Impurity C: Not detected;
Impurity D: Not detected;
Unspecified impurities: not detected;
Total: Not detected.
Water 3.9%~4.4% 4.3%
Sulfated ash NMT 0.1% 0.02%
Assay 99.0% to 100.5%(anhydrous substance) 100.3%
Residual solvents Methano l: NMT 0.3%
Aceton e: NMT 0.5%
Isopropano l: NMT 0.5%
Dichloromethan e: NMT 0.06%
Chlorofor m: NMT 0.006%
Toluen e: NMT 0.089%
Not detected;
0.0005%;
0.2%;
Not detected
Not detected;
Not detected.
Conclusion The test result comply with EP10.0.
CAS No. 66985-17-9
Molecular Formula C20H32BrNO4
Molecular Weight 430.38
Product Name Ipratropium bromide monohydrate
Appearance White Powder
Assay 99%+

 

Melting point: 231 °C

Storage conditions: 2-8°C

Solubility H2O: soluble10mg/mL

Form: powder

Color:white

What is Ipratropium bromide

Ipratropium Bromide is a pharmaceutical ingredient used for for the treatment of chronic obstructive pulmonary disease and acute asthma

Fuction and Application of Ipratropium bromide

Ipratropium bromide (INN, trade names Atrovent, Apovent, Ipraxa, Aerovent and Rinatec) is an anticholinergic drug used for the treatment of chronic obstructive pulmonary disease and acute asthma.

Analysis of Report

Items

Specification

 Result

Assay

99.0%-100.5%

100.2%

Apperance

White or almost white crystalline powder

Almost white crystalline powder

PH

5-7.5

5.9

Water

3.9%-4.4%

4.1%

Related substances

Total impurities≤0.25%

Other unknown inpurity≤0.1%

0.062%

N.D

Sulphated ash

≤0.1%

<0.1%

 

We are at the exhibition every year.

Details

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

 

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