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Home > Products >  Manufacturer Supplying High Quality Sitagliptin Phosphate Monohydrate API with CAS 654671-77-9

Manufacturer Supplying High Quality Sitagliptin Phosphate Monohydrate API with CAS 654671-77-9 CAS NO.654671-77-9

  • FOB Price: USD: 0.02-0.03 /Gram Get Latest Price
  • Min.Order: 1 Gram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Top(1-1000)GramTop(1000-2000)Gram

  • Product Details

Keywords

  • Sitagliptin phosphate monohydrate
  • Sitagliptin Phosphate
  • Sitagliptinphosphatemonohydrate

Quick Details

  • ProName: Manufacturer Supplying High Quality Si...
  • CasNo: 654671-77-9
  • Molecular Formula: C16H20F6N5O6P
  • Appearance: White powder
  • Application: A new type of hypoglycemic drug dipept...
  • DeliveryTime: 3-7days
  • PackAge: bag or barrel or drum
  • Port: Shanghai or Shenzhen or Qingdao
  • ProductionCapacity: 6000 Metric Ton/Day
  • Purity: 99%+
  • Storage: Store at room temperature
  • Transportation: by express or air or sea
  • LimitNum: 1 Gram
  • Moisture Content: <0.001%
  • Impurity: <0.001%
  • Assay: 99%+
  • Shelf Life: 2 years
  • Appearance: White Powder

Superiority

Chemical Name

Sitagliptin phosphate monohydrate

Synonyms

Sitagliptin phosphate hydrate (jan);7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate;3(R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H [1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate;Sitagliptin phosphate for research;Sitagliptin phosphate hydrate;

CAS No.

654671-77-9

Molecular Formula

C16H20F6N5O6P

Molecular Weight

523.32400

PSA

173.84000

LogP

1.66180


Sitagliptin is the first novel dipeptidyl peptidase IV inhibitor from Merck for the treatment of type 2 diabetes without weight gain and the incidence of hypoglycemia was similar to placebo. Sitagliptin acts by enhancing the body's incretin system, which helps to regulate glucose by affecting β and α cells in the pancreas.

Sitagliptin has the effect of lowering blood sugar, with good safety, basically no side effects such as weight gain, nausea, and vomiting, and rarely occurs hypoglycemia, and it is well tolerated by patients. A 24-week randomized, double-blind, placebo-controlled study of 741 patients (HbA1c 8.0%) evaluated the safety and tolerability of sitagliptin. The subjects were divided into 3 groups: sitagliptin 100mg group, 200mg group, once a day; placebo group. Results Maiming, compared with the placebo group, the other 2 groups had no obvious side effects, its safety and tolerance were good, basically no hypoglycemia, no nausea, vomiting, etc., the patient did not increase in weight, the probability of occurrence >2%. However, there are some special adverse reactions that are significantly different from the placebo group, such as constipation, rhinitis, pharyngitis, sore throat, urinary tract infection, myalgia, arthralgia, hypertension, dizziness and other symptoms, but the degree of reaction is mild To moderate, also self-limiting. The results of laboratory tests were basically unremarkable, except that the content of alkaline phosphatase was slightly decreased, and the absolute counts of white blood cells and neutrophils were slightly increased, but they were not accompanied by any clinical symptoms, and may not have significant clinical symptoms. significance.

Q1.Are you a manufacturer or a trading company
A1.Our company is a leading manufacturer specializing in trade and the development, production and marketing of pharmaceutical intermediates and apis for more than 10 years.
Q2.What about the quality of your products
A2.We value quality as life.We strictly control the quality of each process, established a perfect quality control system.
Q3.In the third quarter.What is your minimum order quantity
A3.Our minimum order quantity is 1 gram.
Q4.Fourth quarter.Can you provide free test samples
A4.Yes, we can provide 10g free samples for consumer test.
Q5.What is your delivery time
A5.Delivery takes 2-3 days, depending on the destination.
Q6.What about the mode of transportation
A6.For urgent and light orders, UPS, FedEx, DHL, EMS can be used;For heavier goods, we provide the method of air or sea transportation to consumers.
Q7.So far.How about the terms of payment
A7.We accept T/T,  Paypal, , money gram, etc.
 

Details

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

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