Pharmaceutical Intermediate API Ketoconazole Powder CAS 65277-42-1 99% Ketoconazole Organic Intermediate Medicine Material Food Additive in Stock CAS NO.65277-42-1

 What is Ketoconazole 

Ketoconazole is a broad-spectrum antifungal imidazole, which interferes with the activity of fungal cytochrome P-450 with high selectivity, thereby inhibiting the biosynthesis of ergosterol in fungal cell membranes.

Function of Ketoconazole 

It is effective in the treatment of both shallow and deep fungal infections, and can inhibit the growth of fungi and the transformation from spores to mycelium to prevent further infections. It has antifungal effects on Candida, Fonsecaea, Coccidioides, Histoplasma, Sporothrix and Trichophyton.

Application of Ketoconazole 

Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored tablets that may need to be cut to smaller size for correct dosage.

1. Imidazole antifungal drugs.

2. It is an antifungal drug for the treatment of athlete's foot and excessive dandruff

3. A broad-spectrum antifungal drug that is a CYP3A4 inhibitor

Ketoconazole is an imidazole broad-spectrum antifungal drug, which is sold under the trade names of Jindakning, Miconing and Kening. It inhibits the fungal cell membrane by highly selectively interfering with the activity of fungal cytochrome P-450. Biosynthesis of ergosterol. It is effective for both superficial and deep fungal infections, not only inhibiting the growth of fungi, but also inhibiting the transformation of spores into mycelium, preventing further infection. Low concentration bacteriostatic, high concentration bactericidal. It has antibacterial effect on Candida, Chromophytes, Coccidioides, Histoplasma, Sporothrix and Trichophyton. It is clinically suitable for the treatment of tinea pedis, tinea pedis, tinea pedis, tinea corporis, tinea cruris, oral thrush, tinea versicolor and skin candidiasis. Ketoconazole lotion is used as an external drug for the skin. It is mainly used in clinical treatment and prevention of various infections caused by Malassezia, such as tinea versicolor, seborrheic dermatitis and pityriasis scalp (dandruff), and can quickly relieve the symptoms caused by Scaling and itching due to seborrheic dermatitis and pityriasis scalp.

1. We has 11 years' exporting experience in pharmaceutical ingredient products.

Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Ketoconazole is suitable for the treatment of the following systemic fungal infections:

1. Candidiasis, chronic skin and mucous membrane candidiasis, oral candidiasis, urinary tract candidiasis, chronic and recurrent vaginal candidiasis for which local treatment is ineffective.

2. Dermatitis blastomycosis.

3. Coccidioidomycosis.

4. Histoplasmosis.

5. Color fungal disease.

6. Paracoccidioidomycosis. Dermatomycosis, tinea versicolor and tinea versicolor caused by dermatophytes and yeast, when topical treatment or oral griseofulvin is ineffective, or severe stubborn dermatophyte infection that is difficult to receive griseofulvin treatment, this product can be used treat.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.