Good Quality Factory Supply 99% Purity Raltegravir CAS 518048-05-0 CAS NO.518048-05-0

English name: Raltegravir

CAS number: 518048-05-0

Molecular formula: C20H21FN6O5

Molecular weight: 444.42

EINECS Number: 610-733-3

Melting point: 216°C (Solv:isopropanol(67-63-0))

Density: 1.46±0.1g/cm3(Predicted)

Storage conditions: -20°C Freezer

Solubility: DMSO(Slightly), Methanol(VerySlightly)

Acidity coefficient: (pKa) 4.50 ± 1.00 (Predicted)

Form:Solid

Color: White to Light Beige

Raltegravir, also known as MK-0518, is an antiretroviral drug used to treat HIV infection. Raltegravir is a human immunodeficiency virus (HIV) integrase strand transfer inhibitor (HIV-1 INSTI) with HIV-1 antiviral activity. Raltegravir binds to and inhibits integrase, an HIV enzyme that inserts viral genetic material into the genetic material of the infected human cell. Inhibition of integrase prevents insertion of HIV DNA into the human DNA genome, thus blocking HIV replication. It received approval by the U.S. Food and Drug Administration (FDA) in October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.

Why choose KANAL:

1. quality
our products meet msds safe standard and we have iso and other certificate so you can get high quality products from our company.
2. price
we are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
3.packing
we can do according to the customers' request.
4.transport
ems,dhl, tnt, ups ,fedex, by air, by sea
dhl express, fedex and ems for quantity less than 50kg, usually called as ddu service; 
sea shipping for quantity over 500kg; and air shipping is available for 50kg above;
for high value products, please select air shipping and dhl express for safe;
5.service
we offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
we will try our best to satisfied you.
1. tailor-made for every customers. 
2. third-party test for the products you demand. 
3. test your counter-samples and produce them for you. 
4. best discount for old customers. 

1. We has 11 years' exporting experience in pharmaceutical ingredient products.

Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Raltegravir ,It can be combined with other antiretroviral drugs for the treatment of human immunodeficiency virus (HIV) -1 infection. It slows down HIV-1 infection by inhibiting the HIV integrase required for viral replication. When Rett Kawet with other anti HIV drugs can reduce the number of HIV in blood, and the increase of CD4+T cells known as the number of white blood cells, contribute to the anti infection. Show with Lito Bernard Vee, efavirenz, tenofovir for Ranave, the interaction of the goods and drug resistance no cross resistance and has a synergistic effect with multiple drugs.

Raltegravir (RAL), , used to treat HIV infection.

In a study of the drug as part of combination therapy, raltegravir exhibited potent and durable antiretroviral activity similar to that of efavirenz at 24 and 48 weeks but achieved HIV-1 RNA levels below detection at a more rapid rate. After 24 and 48 weeks of treatment, raltegravir did not result in increased serum levels of total cholesterol, low-density lipoprotein cholesterol, or triglycerides

Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.