For anti-inflammatory CAS 50-02-2 Raw Material Powder Dexamethasone CAS NO.50-02-2

Commonly used its acetate, white or off-white crystal or crystalline powder; odorless, slightly bitter taste. Easily soluble in acetone, soluble in methanol or absolute ethanol, slightly soluble in ethanol or chloroform, very slightly soluble in ether, insoluble in water. Its sodium phosphate is easily soluble in water.

English name: Dexamethasone

CAS number: 50-02-2

Molecular formula: C22H29FO5

Molecular weight: 392.47

EINECS No.: 200-003-9

Melting point: 262-264°C(lit.)

Specific rotation: 75º (c=1, dioxane)

Boiling point: 568.2±50.0°C (Predicted)

Density: 1.1283 (estimate)

Refractive index: 76°(C=1, Dioxane)

Flash point: 9℃ Storage conditions: 2-8°C

Solubility:ethanol:1mg/mL

Form: powder

Acidity coefficient (pKa): 12.13±0.70 (Predicted)

Color: off-white

Water solubility: 10mg/100mL (25ºC)

Sensitivity: Light Sensitive

Dexamethasone is one of the commonly used drugs in clinical practice. It is often used in combination with other drugs in clinical practice, and it has anti-inflammatory, anti-toxic and anti-allergic effects. However, it has no therapeutic effect on the disease, and can only reduce or inhibit the performance of inflammation. Therefore, we must pay attention to clinical medication. Generally, it is not used alone and must be used in conjunction with other drugs to play a better role. The anti-inflammatory effect of this product and the effect of controlling skin allergy are more significant than that of prednisone, while the effect on water and sodium retention and the promotion of potassium excretion is relatively mild, and the inhibitory effect on the pituitary-adrenal cortex axis is stronger. Intramuscular injection of dexamethasone sodium phosphate or dexamethasone acetate, the plasma concentration peaked at 1 hour or 8 hours, respectively.

Dexamethasone (Dexamethasone Sodium Phosphate EP Impurity A) is a glucocorticoid used as an anti-inflammatory agent.

Dexamethasone regulates T cell survival, growth and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase. Mainly used for anti-inflammatory and anti-allergy, suitable for rheumatoid arthritis and other collagen diseases.

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Commonly used its acetate, white or off-white crystal or crystalline powder; odorless, slightly bitter taste. Easily soluble in acetone, soluble in methanol or absolute ethanol, slightly soluble in ethanol or chloroform, very slightly soluble in ether, insoluble in water. Its sodium phosphate is easily soluble in water.
English name: Dexamethasone
CAS number: 50-02-2
Molecular formula: C22H29FO5
Molecular weight: 392.47
EINECS No.: 200-003-9

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


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