Isatis Indigotica Fort Extract Powder CAS 479-41-4 97% Indirubin CAS NO.479-41-4

[English name] Indirubin
[Chemical name] 2- (2-oxo-1H-indol-3-ylidene) -1H-indol-3-one
[Molecular formula] C16H10N2O2
[Molecular weight] 262.26
[CAS Number] 479-41-4
[Detection method] High performance liquid chromatography HPLC
[Specification] ≥97%
[Properties] Dark red needle-like crystals, odorless.
[Source of extraction] Dried leaves of Isatis indigotica Fort
[Storage Method] Keep away from light and store in a sealed place.

[Packing specifications] 1kg / aluminum foil bag, or packaging according to customer requirements, minimum 1g.

Indirubin is an active ingredient of anti-leukemia isolated from dried leaves of Isatis indigotica Fort. For the treatment of chronic myeloid leukemia, the total effective rate was 87.3%. In terms of reducing white blood cells effect, Indirubin is similar to Maryland, but better than Maryland in reducing liver. Its' blood and bone marrow mitigation effect is worse than Maryland, and has no cross tolenrance with Maryland.

Indirubin also has a certain effect on acute myeloid leukemia. It can be used for abnormal myelopathy and eosinophilia. Indirubin has inhibiting effect on a variety of transplanted animal tumors, and can destroy leukemia cells. With the effect of Indirubin, cells of degeneration and necrosis show swelling and soluble necrosis. Through experimental studies it is found that Indirubin can enhance the animal's monocyte-macrophage system's phagocytosis. Indirubin has no direct effect on protein synthesis. Its' inhibition of DNA synthesis is due to inhibition of DNA polymerase, affecting the polymerization of DNA. Indirubin metabolizes in liver and gallbladder after intravenous injection or intragastric administration. After 96 hours 76.03% Indirubin was eliminated by faeces. After taking this product, the mice's blood concentration gradually increased, after 12 hours it reached the peak, slowed down after a month, maintaining a long time. Indirubin is highly distributed in liver, gallbladder and gastrointestinal. Bioavailability was 46.48%.

1. Clearing heat and releasing toxins;
2. Cooling blood and reducing swelling;
3. To be used for treating warm disease & excessive heat, macula, hemoptysis, sore throat & canker sore, and snake bittings;
4. Also to be used for treating therioma, chronic myelocytic leukemia and pancreatic cancer;
5. Can destroy the leukemia cells, anti-tumor effect.

Q1.Are you a manufacturer or a trading company
A1.Our company is a leading manufacturer specializing in trade and the development, production and marketing of pharmaceutical intermediates and apis for more than 10 years.
Q2.What about the quality of your products
A2.We value quality as life.We strictly control the quality of each process, established a perfect quality control system.
Q3.In the third quarter.What is your minimum order quantity
A3.Our minimum order quantity is 1 kilogram.
Q4.Fourth quarter.Can you provide free test samples
A4.Yes, we can provide 10g free samples for consumer test.
Q5.What is your delivery time
A5.Delivery takes 2-3 days, depending on the destination.
Q6.What about the mode of transportation
A6.For urgent and light orders, UPS, FedEx, DHL, EMS can be used;For heavier goods, we provide the method of air or sea transportation to consumers.
Q7.So far.How about the terms of payment
A7.We accept T/T,  Paypal, , money gram, etc.
 

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.