China (Mainland)
99% High Purity GMP factory Tandutinib Manufacturer CAS 387867-13-2 CAS NO.387867-13-2
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Keywords
- Tandutinib
- Bulk Price Tandutinib Manufacturer
- Manufacturer Supply Tandutinib
Quick Details
- ProName: 99% High Purity GMP factory Tandutinib...
- CasNo: 387867-13-2
- Molecular Formula: C31H42N6O4
- Appearance: White to off-white powder
- Application: Anticancer APIs, new immunomodulatory ...
- DeliveryTime: 3-7days
- PackAge: bag or barrel or drum
- Port: Shanghai or Shenzhen or Qingdao
- Purity: 99%+
- Storage: Store at room temperature
- Transportation: by express or air or sea
- LimitNum: 0
- Related Substances: <0.001%
- Residue on Ignition: <0.001%
- Valid Period: 2years
Superiority
Tandutinib is a novel oral small-molecule multi-target receptor tyrosine kinase inhibitor developed by Millennium Pharmaceuticals. , multiple myeloma, and myelodysplastic syndromes. It has inhibitory effects on receptor tyrosine kinases, including FMS-like tyrosine kinase-3 (FLT-3), PDGFR and stem cell factor receptor (c-KitR). Tandutinib inhibits the phosphorylation of FLT-3. In a phase I clinical trial, 40 patients with AML and myelodysplastic syndrome (MDS) were given oral tandutinib, and the results showed that the maximum tolerated dose (MTD) was 525 mg (bid), and showed some activity. Tandutinib is currently in Phase II clinical studies.
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Details
CAS number: 387867-13-2
Molecular formula: C31H42N6O4
Molecular weight: 562.7
Melting point: 177-178°C
Boiling point: 769.5±60.0°C (Predicted)
Density: 1.213±0.06g/cm3(Predicted)
Storage conditions: Sealedindry, Storeinfreezer, under-20°C
Solubility: Chloroform(Slightly), Methanol(Slightly)
Acidity coefficient: (pKa) 13.39±0.70 (Predicted)
Form:Solid
Color: White to Off-White