Lower Price Factory high quality Glipizide Cas 29094-61-9 CAS NO.29094-61-9

Product Description
Glipizide(K 4024; CP 2872) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.Target: Potassium ChannelGlipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. It is classified as a second generation sulfonylurea, which means that it undergoes enterohepatic circulation. Mechanism of action is produced by blocking potassium channels in the beta cells of the islets of Langerhans. By partially blocking the potassium channels, the cell remains depolarized, increasing the time the cell spends in the calcium release stage, which results in signaling leading to calcium influx. The increase in calcium will initiate more inulin release from each beta cell. Sulfonylureas may also cause the decrease of serum glucagon and potentiate the action of inulin at the extrapancreatic tissues
Quick Details
CAS No.:    29094-61-9    Other Names:    Glipizide 29094-61-9    MF:    C21H33N5O4S
EINECS No.:    249-427-6    Place of Origin:    China (Mainland)    Type:    Blood System Agents
Grade Standard:    Medicine Grade, Tech Grade    Usage:    Animal Pharmaceuticals    
Purity:    99% Min    Product Name:    Glipizide
Appearance::    White Crystal Powder    Test method::    HPLC    Service Attitude::    ^_^
MW::    451.5828    Melting point::    208-209°C    Density::    1.29g/cm3
Water solubility::    methnol: 1.9 mg/mL    Refractive index::    1.597    Assay:    99.0~101.0%
 
 
 
Glipizide
 
Introduction:
Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. It is classified as a second generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation sulfonylureas are both more potent and have shorter half-lives than the first-generation sulfonylureas.

 
Specification:
 
Tests    Specifications    Results
Appearance    White or almost white crystalline powder    White crystalline powder
Identification    IR: The IR absorption spectrum of sample corresponds to that of reference one    Complies
Loss on drying    Not more than 0.5%    0.1%
Residue on ignition    Not more than 0.2%    0.03%
Related substances
Impurity A
Impurity X3
Unspecified impurity
Total impurities     
Not more than 0.3%
Not more than 0.15%
Not more than 0.10%
Not more than 0.5%     
0.10%
0.08%
0.04%
0.26%
Impurity B    Not more than 0.01%    N.D
Assay    98.0%~102.0%
( Calculated on dried basis)    99.4%
Conclusion    Complies with EP7.0
Chemical & Physical Properties
Boiling Point    424.5ºC at 760 mmHg
Melting Point    175-176°C
Molecular Formula    C18H28ClNO2
Molecular Weight    325.873
Flash Point    210.5ºC
Exact Mass    325.180847
PSA    29.54000
LogP    4.66410

Why choose KANAL:

1. quality
our products meet msds safe standard and we have iso and other certificate so you can get high quality products from our company.
2. price
we are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
3.packing
we can do according to the customers' request.
4.transport
ems,dhl, tnt, ups ,fedex, by air, by sea
dhl express, fedex and ems for quantity less than 50kg, usually called as ddu service; 
sea shipping for quantity over 500kg; and air shipping is available for 50kg above;
for high value products, please select air shipping and dhl express for safe;
5.service
we offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
we will try our best to satisfied you.
1. tailor-made for every customers. 
2. third-party test for the products you demand. 
3. test your counter-samples and produce them for you. 
4. best discount for old customers. 

1. We has 11 years' exporting experience in pharmaceutical ingredient products.

Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.