High Quality GMP Manufacturer CAS 22494-42-4 Diflunisal CAS NO.22494-42-4

English name: Diflunisal

CAS number: 22494-42-4

Molecular formula: C13H8F2O3

Molecular weight: 250.2

EINECS Number: 245-034-9

Melting point: 207-209°C

Boiling point: 386.9±42.0°C (Predicted)

Density: 1.3505 (estimate)

Storage conditions: Keep in dark place, Sealed in dry, RoomTemperature

Diflunisal, a non-steroidal anti-inflammatory analgesic, is the most promising alternative to aspirin. Clinically used for the treatment of rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, sprains, strains and pain relief. Studies have shown that diflunisal and ibuprofen are equally effective in the treatment of rheumatoid arthritis and degenerative arthritis. In the observation, it was also found that diflunisal was significantly better than ibuprofen in improving the grip strength of patients with rheumatoid arthritis and relieving joint pain and tenderness of rheumatoid arthritis and degenerative arthritis. At the same time, diflunisal can reduce and relieve rheumatoid factor titer and morning stiffness in patients with rheumatoid arthritis. The analgesic effect of diflunisal is 7.5 to 13 times that of aspirin, and its antipyretic effect is 1.4 times that of aspirin. , its therapeutic effect is about 3 times stronger than that of aspirin, so it is suitable for the treatment of rheumatoid arthritis, osteoarthritis and moderate pain caused by muscle sprains, strains, meniscus surgery, orthopaedic and oral surgery, and primary dysmenorrhea ,Worthy of clinical application. Diflunisal was screened from more than 500 salicylic acid derivatives by the US MerckSharp & Dohme company with flunisal as the lead compound, and was launched in 1975. At present, it is one of Merck's varieties with annual sales exceeding 100 million US dollars, and has been listed in more than 70 countries such as the United Kingdom, the United States, Japan, Italy, and France. There are diflunisal tablets and diflunisal capsules approved for production.

1. Antipyretic analgesics, suitable for mild to moderate pain. It is also a drug for the digestive system.

2. Mainly used for the treatment of rheumatoid arthritis and rheumatoid arthritis, back, shoulder, knee, neck strain or sprain and pain caused by tumor surgery, etc.

Q1.Are you a manufacturer or a trading company
A1.Our company is a leading manufacturer specializing in trade and the development, production and marketing of pharmaceutical intermediates and apis for more than 10 years.
Q2.What about the quality of your products
A2.We value quality as life.We strictly control the quality of each process, established a perfect quality control system.
Q3.In the third quarter.What is your minimum order quantity
A3.Our minimum order quantity is 1 gram.
Q4.Fourth quarter.Can you provide free test samples
A4.Yes, we can provide 10g free samples for consumer test.
Q5.What is your delivery time
A5.Delivery takes 2-3 days, depending on the destination.
Q6.What about the mode of transportation
A6.For urgent and light orders, UPS, FedEx, DHL, EMS can be used;For heavier goods, we provide the method of air or sea transportation to consumers.
Q7.So far.How about the terms of payment
A7.We accept T/T,  Paypal, , money gram, etc.
 

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.