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Home > Products >  Bimatoprost CAS 155206-00-1

Bimatoprost CAS 155206-00-1 CAS NO.155206-00-1

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  • Bimatoprost
  • 99% GMP factory Bimatoprost
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Quick Details

  • ProName: Bimatoprost CAS 155206-00-1
  • CasNo: 155206-00-1
  • Molecular Formula: C25H37NO4
  • Appearance: White to off-white powder
  • Application: Bimatoprost is a synthetic prostagland...
  • DeliveryTime: 3-7days
  • PackAge: bag or barrel or drum
  • Port: Shanghai or Shenzhen or Qingdao
  • ProductionCapacity: 6000 Kilogram/Day
  • Purity: 99%+
  • Storage: Store at room temperature
  • Transportation: by express or air or sea
  • LimitNum: 1 Gram
  • Moisture Content: <0.001%

Superiority

English name: Bimatoprost

CAS number: 155206-00-1

Molecular formula: C25H37NO4

Molecular weight: 415.57

EINECS Number: 642-890-9

Melting point: 66-68°C

Boiling point: 629.8±55.0°C (Predicted)

Density: 1.145±0.06g/cm3(Predicted)

Storage conditions: -20°C

Bimatoprost is a prostaglandin that was first used to treat glaucoma and other eye diseases under the name Lumigan. However, during the treatment, the patient unexpectedly noticed a significant increase in the diameter, length and density of her eyelashes. Later, bimatoprost was used in clinical trials for eyelash beauty, and its effectiveness in thickening and thickening eyelashes led allergan, the manufacturer of Lumigen, to introduce Lattise, which was approved by the US FDA in December 2008 as a professional product for darkening and thickening eyelashes.Use in the treatment of glaucoma, can also be used in eyelash growth liquid, concentration of 0.03%.

Olaparib is a PARP inhibitor that also acts on BRCA1 or BRCA2 mutations. Olaparib has little effect on tankyrase-1, and its IC50 value is greater than that. Olaparib concentration of 30-100nM acts on SW620 cells to inactivate PARP-1. BRCA1-deficient cell lines (MDA-MB-463[1] and HCC1937) are oversensitive to Olaparib compared to BRCA1- and BRCA2-sufficient cell lines (Hs578T, MDA-MB-231, T47D) Olaparib inhibits PARP and blocks base excision repaired, resulting in strong sensitivity of KB2P cells to Olaparib. The result is a transition from single-strand breaks to double-strand breaks during DNA replication, thereby activating the BRCA2-dependent recombination pathway.

Bimatoprost is a synthetic prostaglandin F2α derivative that can selectively mimic the effect of prostaglandins produced in the body, increasing the rate of aqueous humor production and reducing the outflow resistance of aqueous humor. It is considered to be the local anti-glaucoma drug with the strongest intraocular pressure lowering effect at present. It is suitable for the treatment of open-angle glaucoma (POAG) or other ocular hypotensive drugs. Hypertension (OHT) patients.

Details

Product Name: Bimatoprost
Synonyms: N-ETHYL-9ALPHA,11ALPHA,15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z, 13E-DIEN-1-AMIDE;LUMIGAN;BIMATOPROST;BIMATOPROST(TM);17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ETHYL AMIDE;BIMATOPROST(LUMIGAN);17-phenyl-tri-norprostaglandin f2α-ethyl amide;(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
CAS: 155206-00-1
MF: C25H37NO4
MW: 415.57
EINECS: 642-890-9
Melting point 66-68°C
Boiling point 629.8±55.0 °C(Predicted)
density 1.145±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
pka 14.25±0.20(Predicted)
form solid
color White to Off-White
Stability: Light Sensitive

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

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