99% N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin Terlipressin acetate API Chemicals CAS 14636-12-5 Terlipressin CAS NO.14636-12-5
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- Min.Order: 1 Gram
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- Product Details
Keywords
- Terlipressin acetate
- Terlipressin
- N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
Quick Details
- ProName: 99% N-(N-(N-Glycylglycyl)glycyl)-8-L-l...
- CasNo: 14636-12-5
- Molecular Formula: C52H74N16O15S2
- Appearance: White powder
- Application: Terlipressin can improve liver and kid...
- DeliveryTime: 3-7days
- PackAge: bag or barrel or drum
- Port: Shanghai or Shenzhen or Qingdao
- ProductionCapacity: 6000 Metric Ton/Day
- Purity: 99%+
- Storage: Store at room temperature
- Transportation: by express or air or sea
- LimitNum: 1 Gram
- Moisture Content: <0.001%
- Impurity: <0.001%
- Assay: 99%+
- Shelf Life: 2 years
- Appearance: White Powder
Superiority
Who are we:
1) Specialized in pharmaceutical and healthcare industrial for 34 years.
2) ISO 9001:2015 & SGS audited supplier .
3) Accept various payment terms : T.T 30-60 days.
4) We have warehouse in USA with quickly shipment .
5) We can do different terms of FOB ,CIF/CIP ,DDP ...
English name: Terlipressin acetate
CAS number: 14636-12-5
Molecular formula: C52H74N16O15S2
Molecular weight: 1227.37
EINECS Number: 238-680-8
Melting point:>170°C(dec.)
Boiling point: 1824.0±65.0°C (Predicted)
Density: 1.46±0.1g/cm3(Predicted)
Terlipressin (trade names Teripress by New Medicon Pharma and Glypressin by Ferring Pharmaceuticals) is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.
Indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used to treat bleeding esophageal varices.
Between the patients with cirrhosis of the liver into the portal circulation of each vein and venous congestion can occur in vascular anastomosis, portal vein pressure rise phenomenon. The most frequently appeared in the azygos vein anastomosis with lower esophageal varices, instant tube.
1. We has 11 years' exporting experience in pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.
2.We can provide you with ten thousands of products of different levels.
3. We offer convenient one-station purchasing service.
(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.
Application
This product is pressurized prodrug hormone, vasopressin glycyl in injection into the blood after enzymatic hydrolysis in the molecule is produced a continuous low level. The portal venous pressure it generates the desired effect, but the changes of arterial blood pressure than the use of vasopressin after much smaller, and the blood of a few do not increase the fibrinolytic. Push once its role can be maintained for about 4 ~ 6h.
Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly "release" the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.
Terlipressin can improve liver and kidney function, reverse HRS, and prolong the survival time of HRS patients, so it prolongs the waiting time for liver transplantation. At the same time, terlipressin is an important treatment drug for patients with esophageal variceal bleeding in emergency situations, and it is the only drug that has been shown to prolong the survival time of patients with esophageal varices bleeding. In addition, terlipressin has a certain effect in the treatment of refractory shock, cirrhotic ascites, intraoperative hypotension and cardiac arrest in children, and has a good clinical application prospect.
Details
Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.
Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.
An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.
1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.
2.We can provide you with ten thousands of products of different levels.
3. We offer convenient one-station purchasing service.
(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.
Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.
The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.