Lower Price Antibiotic Aerosporin Polymyxin B Sulfate CAS 1405-20-5 CAS NO.1405-20-5

English name: Polymyxin B sulfate

CAS number: 1405-20-5

Molecular formula: C56H100N16O17S

Molecular weight: 1301.56

EINECS Number: 215-774-7

Melting point: 217-220°C (dec.)

Storage conditions: 2-8°C

Solubility:H2O:50mg/mL

Acidity coefficient: (pKa) pKa8.9 (Uncertain)

Form: powder

Color: colorless or slightly yellow

PH value: pH (10g/L, 25℃): 4.5～7.0

Optical activity: (opticalactivity)[α]/D20/D(Rotation:-2.3+/-0.2degrees)

Water solubility:Soluble in water at 50mg/ml/n

Merck: 14,7573

Polymyxin B sulfate is similar to polymyxin E, and has inhibitory effect on gram-negative bacilli, such as Escherichia coli, Pseudomonas aeruginosa, paraEscherichia coli, Klebsiella pneumoniae, acidophilus, pertussis bacillus and dysentery bacillus or bactericidal effect. It is mainly used for infection of wounds, urinary tract, eyes, ears, trachea and other parts caused by Pseudomonas aeruginosa and other Pseudomonas. It can also be used for sepsis and peritonitis. As well as aminoglycoside-resistant, third-generation cephalosporin-resistant bacteria and Pseudomonas aeruginosa or other sensitive bacteria caused by serious infections, such as bacteremia, endocarditis, pneumonia, post-burn infection, etc.

1. Biochemical research

2. Polymyxin B is an anti-Gram-negative bacillus polypeptide antibiotic, which can change the membrane structure to leak small molecules and inhibit the growth of Gram-negative bacteria. It has bactericidal effect on Escherichia coli. Binds to the lipid A moiety of bacterial lipopolysaccharides. Small pores are induced in the outer cell membrane. Mode of Action: Binds to and interferes with the permeability of the cytoplasmic membrane. Antimicrobial spectrum: Gram-negative bacteria.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.