High Quality 99% Zolmitriptan CAS 139264-17-8 Bulk Zolmitriptan Powder Price CAS NO.139264-17-8

English name: Zolmitriptan CAS number: 139264-17-8 Molecular formula: C16H21N3O2 Molecular weight: 287.36 EINECS Number: 629-919-0

Melting point: 136-141°C Specific rotation: D22-5.79°(c=0.5 inmethanol) Boiling point: 563.3±38.0°C (Predicted) Density: 1.217±0.06g/cm3(Predicted) Storage conditions: 15-25°C Solubility:Soluble in DMSO at 5mg/ml Acidity coefficient: (pKa) 9.64 (at25℃) Form: powder Color: white to beige Optical activity: (opticalactivity)[α]/D-3to-8°,c=1inmethanol Maximum wavelength: (λmax) 225nm (lit.) Merck: 14, 10189

Zolmitriptan is a highly effective and specific drug for the treatment of acute migraine, which relieves migraine attacks by stimulating 5-HT1 receptors to induce vasoconstriction and inhibit the release of neuropeptides. The results show that zolmitriptan can control the peripheral blood flow of the brain, and can also act on the pain center of the brain, thus playing a role in the treatment of migraine. When the trigeminal nerve is stimulated or a migraine attack occurs, cerebral blood flow increases, calcitonin gene-related peptide (CGRP) is released, and CGRP and vasoactive peptide (VIP) in the external jugular vein increase. Zolmitriptan can pass through the blood-brain barrier and has dual functions of central and peripheral nerves, which can selectively constrict intracranial blood vessels, especially cranial arteries, and control peripheral blood flow. It can also inhibit the release of vasoactive substances such as CGRP, neurotransmitters A and P, make dural artery vasoconstriction, and reduce aseptic inflammation. Studies have shown that zolmitriptan has an inhibitory effect on HVACa2+ ion channels, thereby reducing the release of neurotransmitters (such as CGRP) and playing a role in the treatment of migraine.

For the acute treatment of migraine with or without aura symptoms. About the mechanism of action, uses, synthesis methods, adverse reactions, etc. of zolmitriptan

Service:
1. Supply high quality products with a reasonable price.
2. Keep shipment in time, provide complete customers clearance documents as customs request. 
3. Provide agile and safe payments.
4. We will responsible for all quality issue.
5. Share marketing informations with customers update price in time.
 
FAQ:

1. What's your payment terms
T/T, D/P, L/C, O/A
2. What's your delivery time
Usually we will arrange the shipment within 14 days.
3. How about the packing  
Usually with 25 kg bag/carton/drum. 
4. How about the validity of the products  
Usually 2 or 3 years. 
5. What documents you provide  
Usually, Commerical Invoice, Packing List, Country of Origin, Insurance Policy, Bill of loading, COA , Health certificate. 
6. What is loading port
Usually, Qingdao, Tianjin and Shanghai  

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

[Assay Determination]: 99.0%~101.0% (dries basis)
[Related Substance]:the single impurity≤0.1%, total impurities≤2.0%
[Package and Storage Condition]: 25kg/drum, store and seal away from light