Manufactory Supply: Vonoprazan Fumarate (TAK-438) 99% White Powder CAS 1260141-27-2 CAS NO.1260141-27-2

English name: TAK-438 CAS number: 1260141-27-2 Molecular formula: C21H20FN3O6S Molecular weight: 461.4634032 EINECS Number: 250-635-4 Vonoprazan fumarate (TAK-438, Vonoprazanfumarate) is a new oral anti-gastric acid drug jointly launched by Takeda Pharmaceutical and Otsuka Pharmaceutical. 【Registration classification】Chemical drug category 3.1 【Indications】Used for the treatment of erosive esophagitis, gastric ulcer and duodenal ulcer. On February 28, 2014, Takeda Pharmaceutical submitted a New Drug Application (NDA) for vonoprazan (TAK-438) to the Japanese Ministry of Labor, Health and Welfare (MHLW). Takeda Pharmaceutical has conducted several Phase III clinical trials in Japan to investigate the efficacy of TAK-438 in indications for erosive esophagitis, gastric ulcer, duodenal ulcer and Helicobacter pylori eradication. In clinical trials, compared with the current proton pump inhibitors (PPIs), vonoprazan (TAK-438) has no CYP2C19 metabolism, so it has shown better efficacy in clinical trials: treatment of gastric ulcer/ten The efficacy of duodenal ulcer, reflux esophagitis, and eradication of pyloric screw is better than that of lansoprazole, and it has good tolerance and safety. On December 26, 2014, Vonoprazan fumarate (TAK-438, Vonoprazanfumarate) was approved for marketing in Japan (trade name Takecab) for the treatment of acid-related diseases. Compared with traditional irreversible proton pump inhibitors (such as omeprazole, esomeprazole, etc.), vonoprazan fumarate (Takecab) has the following advantages: (1) Rapid onset of action, and the first day of administration It will achieve the maximum acid-suppressing effect; ② Oral administration is not affected by gastric acid damage, and does not need to be in the form of enteric-coated administration; ③ It has a certain improvement on the phenomenon of acid breakthrough at night.

Treatment of duodenal ulcer, gastric ulcer and reflux esophagitis, gastric or recurrent duodenal ulcer caused by low-dose aspirin. Helicobacter pylori eradication, adjuvant treatment of the following diseases: gastric ulcer, duodenal ulcer, gastric MALT lymphoma, idiopathic thrombocytopenic purpura, early gastric cancer, Helicobacter pylori-infected gastritis.

Q1.Are you a manufacturer or a trading company
A1.Our company is a leading manufacturer specializing in trade and the development, production and marketing of pharmaceutical intermediates and apis for more than 10 years.
Q2.What about the quality of your products
A2.We value quality as life.We strictly control the quality of each process, established a perfect quality control system.
Q3.In the third quarter.What is your minimum order quantity
A3.Our minimum order quantity is 1 gram.
Q4.Fourth quarter.Can you provide free test samples
A4.Yes, we can provide 10g free samples for consumer test.
Q5.What is your delivery time
A5.Delivery takes 2-3 days, depending on the destination.
Q6.What about the mode of transportation
A6.For urgent and light orders, UPS, FedEx, DHL, EMS can be used;For heavier goods, we provide the method of air or sea transportation to consumers.
Q7.So far.How about the terms of payment
A7.We accept T/T,  Paypal, , money gram, etc.
 

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.