Steroids Powder An antineoplastic CAS 107868-30-4 Aromasin Exemestane CAS NO.107868-30-4

English name: Exemestane CAS number: 107868-30-4 Molecular formula: C20H24O2 Molecular weight: 296.4 EINECS Number: 643-090-2

Exemestane is an irreversible steroidal aromatase inhibitor that is structurally similar to its substrate, natural androstenedione. Estrogen deprivation by aromatase inhibition is an effective and alternative approach to the treatment of hormone-dependent breast cancer in postmenopausal women in natural or artificial postmenopausal women whose disease has not progressed despite tamoxifen therapy of advanced breast cancer.

Exemestane is a steroidal aromatase inactivator whose structure is similar to androstenedione, the natural substrate of aromatase, and is a pseudo-substrate of aromatase. Since estrogen in postmenopausal women is mainly produced by androgens (produced by adrenal cortex) under the action of aromatase in peripheral tissues, this product is inactivated by irreversibly binding to the active site of aromatase, thereby significantly Decreases circulating estrogen levels in postmenopausal women. This product has no obvious effect on the biosynthesis of adrenal cortex hormones, even if the concentration is 600 times higher than the concentration that inhibits the effect of aromatase, it has no significant effect on other enzymes in the corticosteroid production pathway.

1. It is suitable for postmenopausal advanced breast cancer with positive estrogen and progesterone receptors. 2. A second-generation aromatase inhibitor for the treatment of metastatic breast cancer and as an adjuvant therapy for early breast cancer. 3. The pharmaceutical raw material is an irreversible steroidal aromatase inactivator, which can inhibit the synthesis of estrogen and reduce the level of estrogen in the blood circulation. It is suitable for postmenopausal advanced breast cancer patients whose disease progresses after tamoxifen treatment.

1, We offer competitive factory price for both wholesalers and retailers.
2, Fast reply for inquiries.
3, Stable Quality, high purity.
4, We offer EXW/FOB/CFR/DAP/DDP trade terms for your option.
5, Fast Delivery for shipment and Safe for destination custom clearance.
6, Free samples.
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8, More than 22 years export experience in this field.

Exemestane is an irreversible steroidal aromatase inhibitor that is structurally similar to its substrate, natural androstenedione. Estrogen deprivation by aromatase inhibition is an effective and alternative approach to the treatment of hormone-dependent breast cancer in postmenopausal women in naturally or artificially postmenopausal women whose disease has not progressed after tamoxifen therapy of advanced breast cancer.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.