INCB28060 CAS:1029712-80-8 Capmatinib CAS NO.1029712-80-8
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- Min.Order: 1 Gram
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- Product Details
Keywords
- Capmatinib
- Capmatinib high purity
- INCB028060
Quick Details
- ProName: INCB28060 CAS:1029712-80-8 Capmatinib
- CasNo: 1029712-80-8
- Molecular Formula: C23H17FN6O
- Appearance: White powder
- Application: Capmatinib is an oral proto-oncogene c...
- DeliveryTime: 3-7days
- PackAge: bag or barrel or drum
- Port: Shanghai or Shenzhen or Qingdao
- ProductionCapacity: 6000 Metric Ton/Day
- Purity: 99%+
- Storage: Store at room temperature
- Transportation: by express or air or sea
- LimitNum: 1 Gram
- Moisture Content: <0.001%
- Impurity: <0.001%
- Assay: 99%+
- Shelf Life: 2 years
- Appearance: White Powder
Superiority
Description
Camatinib (INC280; INCB28060) is a potent, oral, selective, ATP-competitive c-Met kinase inhibitor (IC50=0.13nM). Camatinib can effectively inhibit the proliferation and migration of c-met-dependent tumor cells, and can effectively induce cell apoptosis. Has anti-tumor activity.
Function
Capmatinib selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting the c-Met signal transduction pathway. This may lead to cell death of tumor cells, over-expression of c-met protein or expression of c-met protein that matches the activity, c-met is a receptor tyrosine kinase that is over-expressed or mutated in many tumor cell types. It plays a key role in tumor cell proliferation, survival, invasion, metastasis and tumor angiogenesis.
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Basic information |
Chemical Name | Capmatinib |
Synonyms | INC280;2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide;2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazolo[1,2-b][1,2,4]triazin-2-yl]benzamide;QC-7530;UNII-TY34L4F9OZ;Expand |
CAS No. | 1029712-80-8 |
Molecular Formula | C23H17FN6O |
Molecular Weight | 412.41900 |
PSA | 85.07000 |
LogP | 3.81990 |
Properties
Appearance & Physical State | Yellow solid powder |
Water Solubility | Insoluble |
Soluble | Soluble in DMSO, not in water |
Description
Capmatinib is an oral proto-oncogene c-Met inhibitor with potential anti-chemicalbook tumor activity.Capmatinib is widely used in clinical trials investigating melanoma, gliosarcoma, solid tumors, colorectal cancer and liver damage.
1. We has 11 years' exporting experience in pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.
2.We can provide you with ten thousands of products of different levels.
3. We offer convenient one-station purchasing service.
(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.
Details
Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.
Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.
An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.
1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.
2.We can provide you with ten thousands of products of different levels.
3. We offer convenient one-station purchasing service.
(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.
Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.
The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.