Anti-Cancer Irinotecan / Irinotecan Hydrochloride / Irinotecan HCl CAS#97682-44-5 CAS NO.97682-44-5

Irinotecan is a semi-synthetic derivatives of camptothecin which can be specifically combined with the topoisomerase I. Topoisomerase I induced reversible single-strand breaks, so that double-stranded structure of DNA unwinded. Irinotecan and its active metabolite SN-38 with topoisomerase I-DNA complex binding, thereby preventing the fractured single-stranded nucleic acid to be connected. Existing research suggests that irinotecan cytotoxicity due to DNA synthesis process. Replicase and a topoisomerase I-DNA irinotecan (or SN-38) triple complex interactions, causing DNA double-strand breaks. Mammalian cells can not efficiently repair the DNA double-strand breaks.

English name: Irinotecan CAS Number: 97682-44-5 Molecular formula: C33H38N4O6 Molecular weight: 586.68 EINECS Number: 691-567-9

Large-scale clinical studies have shown that irinotecan hydrochloride has a significant inhibitory effect on a variety of tumors such as colon cancer, small cell lung cancer, rectal cancer, and leukemia, and it is still effective against fluorouracil-resistant cases. Therefore, irinotecan hydrochloride has attracted worldwide attention.

Irinotecan hydrochloride is a light yellow powder with a melting point of 222~223°C.

1. Antitumor drugs. For DNA synthesis inhibitors. It is a semi-synthetic derivative of camptothecin. 2. Anticancer drugs. 3. Antitumor drugs. For DNA synthesis inhibitors. It is a semi-synthetic derivative of camptothecin; used for the preparation of irinotecan hydrochloride and irinotecan hydrochloride trihydrate; anticancer drug. 4. A camptothecin analog, a topoisomerase I inhibitor.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

Product Name:Citalopram hydrobromide
CAS:59729-32-7
MF:C20H22BrFN2O
MW:405.3
EINECS:261-890-6
Mol File:59729-32-7.mol
Melting point:182-188°C
Flash point:9oC
storage temp. -20°C Freezer
solubility H2O: soluble (sparingly)
form powder

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