Berberine HCL High Purity Pharmaceutical Intermediate Berberine Hydrochloride CAS 633-65-8 with Best Price CAS NO.633-65-8

Description
It is effective in treating intestinal infections such as gastroenteritis, bacillary dysentery, ocular conjunctivitis and suppurative otitis media. Recently, it has also been found to block α-receptor and antiarrhythmic effects.

Berberine hydrochloride, also known as berberine hydrochloride, has been used in clinical practice for a long time as a heat-clearing and detoxifying and antibacterial drug. Commonly used in the treatment of bacillary dysentery, acute gastroenteritis, chronic cholecystitis, conjunctivitis, suppurative otitis media and other diseases, all have significant curative effect. Berberine hydrochloride is an isoquinoline alkaloid, which exists in many plants of 4 families and 10 genera including Berberaceae. Berberine can precipitate yellow needle-like crystals from ether. Berberine is a quaternary ammonium alkaloid, and the solubility of its salts in water is relatively small, such as 1:500 for hydrochloride and 1:30 for sulfate.

Berberine hydrochloride has inhibitory effect on Shigella, Escherichia coli, Streptococcus pneumoniae, Staphylococcus aureus, Streptococcus, Typhoid Bacillus and Amoeba. Clinically, it is mainly used for intestinal infection and bacillary dysentery. This product has also been found to have antiarrhythmic effects. Berberine has strong antitumor activity in vitro and in vivo and can induce B16 cell differentiation; it has synergistic effect with cytarabine hydrochloride in vitro

Berberine has antibacterial effects on hemolytic streptococcus, staphylococcus aureus, gonococcus, and Freund, Shigella Shigella, and enhances leukocyte phagocytosis. Berberine hydrochloride (commonly known as berberine hydrochloride) has been widely used in the treatment of gastroenteritis, bacillary dysentery, etc., and also has certain curative effects on tuberculosis, scarlet fever, acute tonsillitis and respiratory tract infections.

1. It is effective in the treatment of intestinal infections such as gastroenteritis, bacillary dysentery, ocular conjunctivitis, and suppurative otitis media. Recently, this product has also been found to block α-receptors and have anti-arrhythmic effects. 2. It is used for the test of nitrate; it is used clinically as an antibacterial drug. 3. APIs mainly used for intestinal infections such as gastroenteritis and bacillary dysentery caused by sensitive pathogens 4. It has a weak inhibitory effect on bacteria (mainly dysentery, Escherichia coli, Staphylococcus aureus), and reduces the number of fimbriae on the surface of the bacterial body, making it difficult for bacteria to attach to human cells, and can make the stomach and duodenum. of peptic ulcers are relieved. 5. Antibacterials, used to treat intestinal infections caused by Shigella

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

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Chemical Name Pirarubicin
Synonyms(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; Pinorubicin; Therarubicin;
CAS Number 72496-41-4
Molecular Formula C32H37NO12
Appearance Orange to Red Solid
Melting Point>175°C (dec.)
Molecular Weight 627.64
StorageHygroscopic, -20C Freezer, Under Inert Atmosphere
SolubilityChloroform (Slightly), Meth (Slightly, Heated)
StabilityHygroscopic
CategoryStandards; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsStructural analog of Doxorubicin. Antineoplastic.
ReferencesUmezawa, H., et al.: J. Antibiot., 32, 1082 (1979), Majima, H., et al.: Biomed. Pharmacother., 41, 237 (1987), Miller, A.A., et al.: Cancer Res., 47, 1461 (1987), Fallik, D., et al.: Ann. Ocol., 14, 856 (2003),