Lower Price Factory Supply Bulk Spironolactone / Pharmaceutical Chemical CAS 52-01-7 Powder CAS NO.52-01-7

Physical Characters and specifications

• Product name	Spironolactones
  CAS No.	52-01-7
  Molecular Formula	C24H32O4S
  Molecular weight	416.58
  Grade Standard	Medicine Grade
  COA	Avaliable

Product introduction
Spironolactone, also known as spironolactone, is a kind of potassium preserving diuretic drug. It competes with aldosterone in the cortical epithelial cells of distal tubules and collecting ducts for the aldosterone receptor in the target cells, so as to inhibit the role of aldosterone in promoting sodium and potassium exchange, increase the excretion of sodium chloride and have a diuretic effect, while potassium ions can be retained. Therefore, spironolactone is a kind of potassium preserving diuretic drug.



Product application
Aldactone removes excess fluid from the body in congestive heart failure, cirrhosis of the liver, and kidney disease.

It also can be used in combination with other drugs to treat elevated blood pressure, and for treating diuretic-induced low potassium (hypokalemia).

Aldactone also is used to counteract the effects of excessive adrenal aldosterone production (hyperaldosteronism). Aldosterone overproduction can occur from a tumor in the adrenal gland or enlarged adrenal glands (hyperplasia of the adrenal glands).

Spironolactone is a weak potassium-sparing diuretic, also known as spironolactone, spironolactone, white or off-white fine crystalline powder, slightly bitter, odorless or slightly mercaptan odor. It is easily soluble in chloroform, insoluble in water, soluble in ethanol, and easily soluble in benzene or ethyl acetate. The chemical structure is similar to aldosterone, and it can compete with aldosterone for aldosterone receptors in the cytoplasm of distal convoluted tubules and collecting ducts, affecting the binding of aldosterone and receptors, thereby hindering the synthesis of aldosterone-induced protein, thereby inhibiting K+-Na+ exchange and reducing potassium excretion. , acts as a potassium-sparing diuretic

1. Used as a diuretic

2.Itisasynthetic17-lactonesteroidwhichisarenalcompetitivealdosteroneantagonistinaclassofpharmaceuticalscalledpotassium-sparingdiuretics,usedprimarilytotreatascitesinpatientswithliverdisease,low-reninhypertension,hypokalemia

3. Active metabolite of lactone (spironolactone). Inhibits aldosterone biosynthesis. Blockers of the ouabain effect

4. A low-efficiency diuretic whose structure is similar to aldosterone and is a competitive inhibitor of aldosterone

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

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Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.