Levobupivacaine Hydrochloride/Levobupivacaine HCl Powder CAS 27262-48-2 for Local Anesthetic CAS NO.27262-48-2

1. Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.
2. The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and
transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia.
In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.
3.Left bupivacaine has been studied in surgical anesthesia and pain management. Can be used for local infiltration,epidural, intrathecal and peripheral nerve block. For epidural analgesia, can be given clonidine. The double-blind comparison of bupivacaine and bupivacaine showed similar anesthetic effects.

English name: Levobupivacaine hydrochloride CAS number: 27262-48-2 Molecular formula: C18H29ClN2O Molecular weight: 324.89 EINECS Number: 1308068-626-2

Melting point 254 °C (dec.)(lit.) Specific optical rotation -12.5 º (c=2, water) Storage conditions 2-8°C Solubility H2O: soluble20mg/mL, clear form powder color white to beige

Levobupivacaine is an amide local anesthetic

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