Pharmaceutical Intermediate Anti Cancer API High Quality Best Price CAS 231277-92-2 Lapatinib CAS NO.231277-92-2

Description:

Name: Lapatinib
English synonym: Tykerb
CAS Number: 231277-92-2
Molecular formula: C29H26ClFN4O4S
Molecular weight: 581.06
EINECS number: 1806241-263-5

Boiling point: 750.7±60.0°C(Predicted)
Density: 1.381±0.06g/cm3(Predicted)
Storage conditions: Keep in dark place, Sealed in dry, 2-8°C
Acidity coefficient (pKa): 6.34±0.19(Predicted)

Function:

Lapatinib is an oral reversible small molecule tyrosine kinase inhibitor targeting HER-1/HER-2. Lapatinib has a different mechanism of action than the humanized monoclonal antibody drug Herceptin that has been approved for marketing. It can down-regulate cell proliferation signals by double-blocking the HER-1/HER-2 pathway. The clinical indication is the combination of capecitabine in the treatment of advanced or metastatic breast cancer with overexpression of HER2 and previous treatments including anthracyclines, taxanes and trastuzumab. The effective rate of advanced first-line monotherapy is about 12~24%, general clinical guidelines recommend second-line medication, and the effective rate of combined treatment with capecitabine is about 26~33%, and the clinical benefit rate is as high as 71.3%, which is also the most commonly used Of lapatinib combined with chemotherapy.

1. We has 11 years' exporting experience in pharmaceutical ingredient products.

Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.