Bulk in Stock Bivalirudin Powder Buy Online with Good Price CAS: 128270-60-0 CAS NO.128270-60-0

English name: Bivalirudin

CAS number: 128270-60-0

Molecular formula: C98H138N24O33

Molecular weight: 2180.29

EINECS Number: 274-570-6

Density: 1.52±0.1 g/cm3(Predicted)

Storage conditions: -20°C

Form: powder

Color: white to off-white

Bivalirudin is a new synthetic anticoagulant drug, which is a direct, specific and reversible inhibitor of thrombin. It was initially successfully developed by the Swiss company Biogen, and was later transferred to the Medicines Company of the United States. It was approved for listing in the United States in 2000. Its anticoagulant component is a 20-peptide compound derived from hirudin. Whether it is thrombin in the blood circulation or thrombin bound to the thrombus, bivalirudin can specifically bind to its catalytic site and anion binding site, thereby directly inhibiting the activity of thrombin, and its effect is short-lived ,reversible. Early clinical studies have shown that bivalirudin anticoagulation is effective and has a lower incidence of bleeding events, and it is safer to use than traditional heparin anticoagulation. It is mainly used to prevent ischemic complications before and after angioplasty intervention for unstable angina pectoris. In vitro, this product has inhibitory effect on both soluble and thrombus-bound thrombin, which is not affected by the product released by platelets, and prolongs the activated partial thromboplastin time of normal human plasma in a dose-dependent manner. Enzyme time and prothrombin time. For patients with unstable angina pectoris undergoing percutaneous coronary intervention (PCI). In 2010, the number of PCI operations in China reached 300,000, with a compound annual growth rate of over 30%. It can be seen that the sales prospect of bivalirudin after its listing is considerable. Clinical experiments have shown that in the peri-PCI application, the efficacy of bivalirudin is better than the current mainstream combination of unfractionated heparin/low molecular weight heparin + platelet glycoprotein receptor antagonist, especially the bleeding risk is significantly reduced, which greatly improves the use of anticoagulants. Safety: (1) It can significantly reduce the incidence of bleeding in patients with elective PCI, and the risk of total clinical outcomes is reduced by 14%. (2) Does not cause antibody-mediated thrombocytopenia. (3) Reversible combination with thrombin, short half-life, ischemia and hemorrhagic complications are not easy to occur. (4) The main excretion does not pass through the kidney, so it can be safely used in patients with renal impairment

As an alternative to unfractionated heparin and platelet glycoprotein IIb/IIIa antagonists

Why choose KANAL:

1. quality
our products meet msds safe standard and we have iso and other certificate so you can get high quality products from our company.
2. price
we are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
3.packing
we can do according to the customers' request.
4.transport
ems,dhl, tnt, ups ,fedex, by air, by sea
dhl express, fedex and ems for quantity less than 50kg, usually called as ddu service; 
sea shipping for quantity over 500kg; and air shipping is available for 50kg above;
for high value products, please select air shipping and dhl express for safe;
5.service
we offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
we will try our best to satisfied you.
1. tailor-made for every customers. 
2. third-party test for the products you demand. 
3. test your counter-samples and produce them for you. 
4. best discount for old customers. 

1. We has 11 years' exporting experience in pharmaceutical ingredient products.

Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.